Author

W. E. Childers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Roth· 2 shared B. S. Pybus· 2 shared D. J. Colussi· 2 shared J. Gordon· 2 shared J. J. Siekierka· 2 shared M. L. de Souza· 2 shared M. L. Gonzalez· 2 shared P. Bhanot· 2 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Roth

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Discovery of imidazole-based inhibitors of P. falciparum cGMP-dependent protein kinase

R. R. Yadav, M. L. de Souza, M. L. Gonzalez, S. U. Mahmood, T. Eck, T. Kreiss, S. O. Aylor, A. Roth, P. Lee, B. S. Pybus, D. J. Colussi, W. E. Childers, J. Gordon, J. J. Siekierka, P. Bhanot, D. P. Rotella

The paper identifies imidazole-based inhibitors of PfPKG with good potency and low hERG activity against multiple Plasmodium species.

bioRxiv · Nov 5, 2021 · PreprintPharmacology & Toxicology

Discovery of novel potent, cell-permeable inhibitors of P. falciparum cGMP-dependent protein kinase.

R. R. Y. Bheemanaboina, M. L. Gonzalez, S. U. Mahmood, T. Eck, T. Kreiss, M. L. de Souza, S. O. Aylor, A. Roth, P. Lee, B. S. Pybus, P. Bhanot, D. J. Colussi, W. E. Childers, J. Gordon, J. J. Siekierka, D. Rotella

The paper reports the discovery and optimization of novel PfPKG inhibitors with good potency, low hERG activity, and anti-parasitic activity.

bioRxiv · Aug 24, 2021 · PreprintPharmacology & Toxicology