Solute exchange through gap junctions lessens the adverse effects of inactivating mutations in metabolite-handling genes
S. Monterisi, J. Michl, A. E. Hill, A. Hulikova, G. Abdullayeva, W. F. Bodmer, P. Swietach
The paper shows that gap junction-mediated metabolite exchange rescues functional defects caused by inactivating mutations in metabolite-handling genes in colorectal cancer cells.
bioRxiv · Mar 15, 2022Cancer Biology