W. Goessling

A machine learning liver-on-a-chip system for safer drug formulation

This paper develops a liver-on-a-chip system combined with machine learning to model drug metabolism and identify excipients that reduce hepatotoxicity in vivo.

Quantitative intravital imaging reveals in vivo dynamics of physiological-stress induced mitophagy.

This study uses intravital imaging in zebrafish to show that fasting and hypoxia induce mitophagy, with bnip3 as the key regulator in muscle.