W. J. Jaremko

Pre-Steady-State Kinetic Characterization of an Antibiotic-Resistant Mutation of Staphylococcus aureus DNA Polymerase PolC

This paper characterizes the kinetic effects of an antibiotic-resistant mutation in Staphylococcus aureus DNA polymerase PolC, showing reduced drug binding and replication efficiency.

Heterotrimeric PCNA Increases the Activity and Fidelity of Dbh, a Y-family Translesion DNA Polymerase Prone to Creating Single-Base Deletion Mutations

This paper shows that PCNA-123 increases the fidelity and activity of Dbh, a DNA polymerase prone to deletions, by promoting correct nucleotide incorporation and requiring a minimal DNA duplex length.