DNP-assisted solid-state NMR enables detection of proteins at nanomolar concentrations in fully protonated cellular environments
W. N. Costello, Y. Xiao, F. Mentink-Vigier, J. Kragelj, K. K. Frederick
This paper demonstrates that DNP-assisted solid-state NMR can detect proteins at nanomolar concentrations in fully protonated cellular environments using isotopically enriched yeast prion protein.
bioRxiv · Feb 20, 2023Biophysics