MEK1/2 and ERK1/2 mediated lung endothelial injury and altered hemostasis promote diffuse alveolar hemorrhage in murine lupus
H. Zhuang, S. Han, N. S. Harris, W. Reeves
This study shows that MEK1/2-ERK1/2 inhibition prevents diffuse alveolar hemorrhage in lupus-prone mice by reducing endothelial injury and restoring hemostasis.
bioRxiv · May 7, 2024Immunology