H. Zhuang

A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation

This study identifies how the bacterial effector RipE1 stabilizes by hijacking plant ubiquitin proteases and phosphorylation, avoiding degradation and promoting bacterial survival.

m6A RNA methylation impairs gene expression variability and reproductive thermotolerance in Arabidopsis

This study shows that m6A RNA methylation reduces gene expression variability and impairs reproductive thermotolerance in Arabidopsis under heat stress.

Two subsets of circulating Ly6Clo monocytes distinguished by CD138 (syndecan-1) expression and Nr4a1 dependence in pristane-treated mice

This study identifies two subsets of Ly6Clo monocytes in pristane-treated mice, showing that CD138+ monocytes are linked to lung disease and depend on Nr4a1 for their function.

Inhibition of SAR S-CoV-2 infection and replication by lactoferrin, MUC1 and α-lactalbumin identified in human breastmilk

This study identifies lactoferrin, MUC1, and α-lactalbumin in human breastmilk as antiviral components that inhibit SARS-CoV-2 infection and replication, including variants.

SARS-CoV-2 and Malayan pangolin coronavirus infect human endoderm, ectoderm and induced lung progenitor cells

This study shows SARS-CoV-2 and GX_P2V can infect human endoderm, ectoderm, and lung progenitor cells derived from hESCs, with some infections blocked by whey protein and Remdesivir.

The effect of whey protein on viral infection and replication of SARS-CoV-2 and pangolin coronavirus in vitro

This study shows that whey protein from human and other animal milk inhibits SARS-CoV-2 and GX_P2V in vitro by blocking viral attachment, entry, and replication.

SGT1 is not required for bacterial PAMP-triggered immunity

This study shows that SGT1 is not required for bacterial PAMP-triggered immunity in Nicotiana benthamiana and Arabidopsis.

Intra-strain elicitation and suppression of plant immunity by Ralstonia solanacearum type-III effectors in Nicotiana benthamiana

This study investigates how Ralstonia solanacearum uses effector proteins to elicit and suppress plant immunity in Nicotiana benthamiana.