W. S. Tan

Host cell factors important for BHV-1 cell entry revealed by genome-wide CRISPR knockout screen

The paper identifies host factors critical for BHV-1 entry using CRISPR knockout screens and validates them with a new CRISPRi system.

Genome-wide CRISPR knockout screen reveals membrane tethering complexes EARP and GARP important for Bovine Herpes Virus Type 1 replication

The paper uses a genome-wide CRISPR knockout screen to identify host genes important for Bovine Herpes Virus Type 1 replication, finding that EARP and GARP membrane tethering complexes are critical for viral replication.

Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer Samples into Molecular Subtypes

The paper validates a NanoString-based biomarker assay for classifying colorectal cancer samples into molecular subtypes with high concordance across platforms and tissue types.

Structure of the Macrobrachium rosenbergii Nodavirus: A new genus within the Nodaviridae?

This paper presents the atomic-resolution structure of Macrobrachium rosenbergii nodavirus (MrNV) using cryoEM, revealing a unique T=3 capsid with dimeric spikes and structural similarities to Tombusviridae, challenging its taxonomic classification.

Cryo-Electron Microscopy Structure of the Macrobrachium Rosenbergii Nodavirus Capsid at 7 Angstroms Resolution

The paper determines the 7 angstrom resolution cryo-EM structure of MrNV VLPs, revealing a novel capsid organization distinct from other nodaviruses.