A novel strategy for single-cell metabolic analysis highlights dynamic changes in immune subpopulations
P. J. Ahl, R. A. Hopkins, W. W. Xiang, B. Au, N. Kaliaperumal, A.-M. Fairhurst, J. E. Connolly
The paper introduces Met-Flow, a flow cytometry-based method to analyze single-cell metabolism in immune cells, revealing that glucose restriction and metabolic remodeling drive the expansion of inflammatory central memory T cells.
bioRxiv · Jan 21, 2020Immunology