Muscle FOXO-specific overexpression and endurance exercise protects skeletal muscle and heart from defects caused by a high-fat diet in young Drosophila
D. t. Wen, Y.-l. Chen, W.-q. Hou
This study shows that muscle FOXO overexpression and endurance exercise protect skeletal and heart muscle from high-fat diet-induced defects in Drosophila by enhancing antioxidant pathways and lipid catabolism.
bioRxiv · Sep 5, 2022 · PreprintPhysiology