phospho-ERK is a response biomarker to a combination of sorafenib and MEK inhibition in liver cancer
R. R. Bernards, C. Wang, H. Jin, D. Gao, B. Evers, G. Jin, Z. Xue, L. Wang, R. Beijersbergen, W.-X. Qin
This study identifies phospho-ERK as a biomarker for response to sorafenib and MEK inhibition in liver cancer, showing synergistic effects in tumors with high phospho-ERK levels.
bioRxiv · Jan 23, 2018Cancer Biology