Differential Requirement of DICER1 Activity during Development of Mitral and Tricuspid Valves
Shun Yan, Yin Peng, Jin Ying Lu, Saima Shakil, Yang Shi, David K. Crossman, Walter H. Johnson, Shanrun Liu, Donald G. Rokosh, Joy Lincoln, Qin Wang, Kai Jiao
The paper shows that DICER1 activity is essential for mitral valve development but not tricuspid valve development, revealing miRNA-mediated gene regulation as a differential mechanism.
Journal of Cell Science · Aug 10, 2022Peer-reviewedDevelopmental Biology