Assessing bactericidal dynamics of persister-manifested clinical isolates in the presence of macrophages and antibiotics
Jia Hao Yeo, Nasren Begam, Wan Ting Leow, Zhong Hui Yang, Andrea Lay‐Hoon Kwa
This study examines how meropenem affects persister-manifested clinical isolates in macrophages, finding that antibiotics do not significantly reduce bacterial load and may have variable bactericidal effects depending on infection severity.
bioRxiv · Dec 25, 2025 · PreprintImmunology