Author

Zhong Hui Yang

Genomics Institute of the Novartis Research FoundationORCID 0000-0002-9146-0875Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Amanda K. LukensiD· 1 shared Andrea Lay‐Hoon KwaiD· 1 shared Annie N. CowelliD· 1 shared Christin ReimeriD· 1 shared Christine H. TengiD· 1 shared Daniel E. GoldbergiD· 1 shared David A. FidockiD· 1 shared Dionicio R. SiegeliD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Amanda K. LukensORCID

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2 papers

Recent·Most cited

Assessing bactericidal dynamics of persister-manifested clinical isolates in the presence of macrophages and antibiotics

Jia Hao Yeo, Nasren Begam, Wan Ting Leow, Zhong Hui Yang, Andrea Lay‐Hoon Kwa

This study examines how meropenem affects persister-manifested clinical isolates in macrophages, finding that antibiotics do not significantly reduce bacterial load and may have variable bactericidal effects depending on infection severity.

bioRxiv · Dec 25, 2025 · PreprintImmunology

Mapping The Malaria Parasite Drug-Able Genome Using In Vitro Evolution And Chemogenomics

Annie N. Cowell, Eva S. Istvan, Amanda K. Lukens, Marı́a G. Gómez-Lorenzo, Manu Vanaerschot, Tomoyo Sakata, Erika L. Flannery, Pamela Magistrado-Coxen, Matthew Abraham, Gregory LaMonte, Roy M. Williams, Virginia Franco, María Linares, Ignacio Arriaga, Selina E. R. Bopp, , Elizabeth A. Winzeler

Whole genome sequencing reveals how Plasmodium falciparum evolves resistance to diverse compounds and identifies new antimalarial drug targets.

bioRxiv · May 22, 2017 · PreprintGenomics