Upstream open reading frames dynamically modulate CLOCK protein translation to regulate circadian rhythm and sleep
Yuanqiang Sun, Ke Shui, Qinyu Li, Chenlu Liu, Wanting Jin, Jian‐Quan Ni, Jian Lü, Luoying Zhang
This study shows that uORFs in the Clock gene regulate circadian rhythm and sleep by modulating CLK protein translation in Drosophila.
PLoS Biology · May 12, 2025Peer-reviewedNeuroscience