Epigenetic activation of CHST2 by promoter hypomethylation promotes progression of triple-negative breast cancer
Shukun Qu, Kangning Li, Lili Fan, Chenxue Miao, Weiyu Wang, Xu Wang, Guang Song
This study identifies CHST2 as an epigenetically activated gene in TNBC that promotes invasion and poor prognosis through promoter hypomethylation and sulfotransferase activity.
bioRxiv · Feb 14, 2026 · PreprintCancer Biology