NeuroscienceMolecular PsychiatryPeer-reviewed
Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling
Alexis S. Zajicek, Hongyu Ruan, Huihui Dai…·Wei‐Dong Yao
This study shows CYLD promotes synapse pruning and weakening via Akt-mTOR-autophagy signaling, leading to behavioral and synaptic deficits in mice.
35 citations