Author

Hongyu Ruan

SUNY Upstate Medical UniversityORCID 0000-0003-1130-2189Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Hongyu Ruan1 paper · University of Iowa

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Huihui Dai· 2 shared Wei‐Dong YaoiD· 2 shared Alexis S. Zajicek· 1 shared Behnam JavidfariD· 1 shared Hannah L. PhillipsiD· 1 shared Mary Catherine SkolfieldiD· 1 shared Qi Ma· 1 shared Schahram AkbarianiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersNeuroscience

Huihui Dai

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 19, 2023

USP48/USP31 Is a Nuclear Deubiquitinase that Potently Regulates Synapse Remodeling

Qi Ma, Hongyu Ruan, Huihui Dai, Wei‐Dong Yao

This study identifies USP48 as a nuclear deubiquitinase that regulates synapse remodeling by promoting spine pruning and reducing synaptic protein clustering.

3 citations

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceMolecular PsychiatryPeer-reviewedApr 21, 2022

Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling

Alexis S. Zajicek, Hongyu Ruan, Huihui Dai…·Wei‐Dong Yao

This study shows CYLD promotes synapse pruning and weakening via Akt-mTOR-autophagy signaling, leading to behavioral and synaptic deficits in mice.

35 citations

mouseexperimental assay

𝕏 PostBluesky