Author

Wenhua Sun

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Research Focus:differential expression· 2 Assay:GWAS summary statistics· 2 Assay:scRNA-seq· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Thomas GasseriD· 4 shared Benjamin RöebeniD· 2 shared Claudia SchulteiD· 2 shared Isabel WursteriD· 2 shared Kathrin BrockmanniD· 2 shared Manu SharmaiD· 2 shared Manuela M. X. TaniD· 2 shared Mohammad Dehestani· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersGenetic & Genomic Medicine

Thomas GasserORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lysosomal polygenic risk score in Parkinson's disease across populations.

Wenhua Sun, Kathrin Brockmann, Isabel Wurster, Roswitha Kemmner, Benjamin Röeben, Reda Skaiene, Stefanie Lerche, Claudia Schulte, Thomas Gasser, Manuela M. X. Tan, the Global Parkinson’s Genetic Program (GP2)

This study evaluates the performance of a lysosomal polygenic risk score (lyso-PRS) for Parkinson's disease risk across populations and its association with clinical outcomes in Europeans.

medRxiv · Sep 15, 2026 · PreprintGenetic & Genomic Medicine

Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation

Nasser Karmali, Wiebke Kessler, Mohammad Dehestani, Wenhua Sun, Layla Drwesh, Polina Volos, Stanislav Tsitkov, Ashutosh Dhingra, Christian Thomas, Salvador Rodrı́guez-Nieto, Julia Tietz, David Schafflick, Noémia Fernandes, Julia Fitzgerald, Ernest Fraenkel, , Vikas Bansal

The paper investigates transcriptomic changes in oligodendroglial lineage cells from PD patient-iPSCs with LRRK2-G2019S mutation, identifying altered pathways and signaling in OPCs and ODCs.

iScience · Jun 19, 2026Peer-reviewedNeuroscience

Unraveling the Genetic Overlap Between Parkinson's Disease and Schizophrenia Through Genome-wide Association and Cell-Type Specific Transcriptomic Analysis

Wenhua Sun, Mohammad Dehestani, Alice Braun, Nasser Karmali, Isabel Wurster, Benjamin Röeben, Roswitha Kemmner, Kathrin Brockmann, Manu Sharma, Marina Mitjans, Fabian Streit, Thomas Gasser, Vikas Bansal

This study identifies shared genetic loci between Parkinson's disease and schizophrenia using GWAS and scRNA-seq, highlighting RAI1's role in mitochondrial dysfunction and non-motor symptoms.

medRxiv · Jun 16, 2026 · PreprintGenetic & Genomic Medicine

TMEM175, SCARB2 and CTSB associations with Parkinson's disease risk across populations.

Wenhua Sun, Claudia Schulte, Thomas Gasser, Manuela M. X. Tan, the Global Parkinson’s Genetic Program (GP2), Lasse Pihlstrøm, Pedro Chaná, Yeajin Song, Sara Bandrés‐Ciga, Cornelis Blauwendraat, Andrew Singleton, Mike A. Nalls, Hampton L. Leonard, Mie Rizig, Hirotaka Iwaki, , Rejko Krüger

This study identifies genetic associations between lysosomal genes and Parkinson's disease risk across diverse populations using GWAS and whole genome sequencing data.

npj Parkinson s Disease · Dec 2, 2025Peer-reviewedGenetic & Genomic Medicine