Author

Noémia Fernandes

German Center for Neurodegenerative DiseasesORCID 0000-0003-1951-7766Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Ashutosh DhingraiD· 3 shared Patrizia RizzuiD· 3 shared Peter HeutinkiD· 3 shared Anastasia IllarionovaiD· 2 shared Cornelis BlauwendraatiD· 2 shared David Wesley CraigiD· 2 shared Eldem SadikoglouiD· 2 shared Natalia SavytskaiD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersNeuroscience

Ashutosh DhingraORCID

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4 papers

Recent·Most cited

NeuroscienceiSciencePeer-reviewedJun 19, 2026

Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation

Nasser Karmali, Wiebke Kessler, Mohammad Dehestani…·Vikas Bansal

The paper investigates transcriptomic changes in oligodendroglial lineage cells from PD patient-iPSCs with LRRK2-G2019S mutation, identifying altered pathways and signaling in OPCs and ODCs.

DOI 10.1016/j.isci.2026.116368

humanscRNA-seq

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NeuroscienceCell Death and DiseasePeer-reviewedNov 13, 2025

Rescue of the increased susceptibility to Mild Chronic Oxidative Stress of iNeurons carrying the MAPT Chromosome 17q21.3 H1/H1 risk allele by FDA-approved compounds

Eldem Sadikoglou, Daniel Domingo‐Fernándéz, Natalia Savytska…·Peter Heutink

The paper investigates how the H1/H1 risk allele at the MAPT locus increases susceptibility to mild chronic oxidative stress in iNeurons and identifies FDA-approved compounds that rescue this vulnerability.

DOI 10.1038/s41419-025-08147-1

humanexperimental assay

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NeuroscienceScientific DataPeer-reviewedDec 1, 2023

A multi-omics dataset for the analysis Frontotemporal Dementia genetic subtypes

Kevin Menden, Margherita Francescatto, Tenzin Nyima…·Peter Heutink

The paper presents a multi-omics dataset for genetic subtypes of frontotemporal dementia to identify molecular mechanisms disrupted in the disease.

24 citations

humanbulk RNA-seq

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GenomicsCell GenomicsPeer-reviewedFeb 6, 2023

The Foundational data initiative for Parkinsons disease (FOUNDIN-PD): enabling efficient translation from genetic maps to mechanism

Elisângela Bressan, Xylena Reed, Vikas Bansal…·Cornelis Blauwendraat

The paper presents a multi-layered molecular dataset from iPSC-derived dopaminergic neurons to model Parkinson's disease genetic risk and provides a data browser for accessing these resources.

53 citationstop 1%

humanbulk RNA-seq

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