Author

Nasser Karmali

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Mohammad Dehestani· 2 shared Nisha Mohd RafiqiD· 2 shared Thomas GasseriD· 2 shared Vikas BansaliD· 2 shared Wenhua Sun· 2 shared Alice BrauniD· 1 shared Ashutosh DhingraiD· 1 shared Atsushi SaitoiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Mohammad Dehestani

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation

Nasser Karmali, Wiebke Kessler, Mohammad Dehestani, Wenhua Sun, Layla Drwesh, Polina Volos, Stanislav Tsitkov, Ashutosh Dhingra, Christian Thomas, Salvador Rodrı́guez-Nieto, Julia Tietz, David Schafflick, Noémia Fernandes, Julia Fitzgerald, Ernest Fraenkel, , Vikas Bansal

The paper investigates transcriptomic changes in oligodendroglial lineage cells from PD patient-iPSCs with LRRK2-G2019S mutation, identifying altered pathways and signaling in OPCs and ODCs.

iScience · Jun 19, 2026Peer-reviewedNeuroscience

Unraveling the Genetic Overlap Between Parkinson's Disease and Schizophrenia Through Genome-wide Association and Cell-Type Specific Transcriptomic Analysis

Wenhua Sun, Mohammad Dehestani, Alice Braun, Nasser Karmali, Isabel Wurster, Benjamin Röeben, Roswitha Kemmner, Kathrin Brockmann, Manu Sharma, Marina Mitjans, Fabian Streit, Thomas Gasser, Vikas Bansal

This study identifies shared genetic loci between Parkinson's disease and schizophrenia using GWAS and scRNA-seq, highlighting RAI1's role in mitochondrial dysfunction and non-motor symptoms.

medRxiv · Jun 16, 2026 · PreprintGenetic & Genomic Medicine

Dopamine vesicles are specified by mechanisms overriding canonical synaptic vesicle size constraints

Kenshiro Fujise, Nasser Karmali, Jaya Mishra, Himari Kimura, Tomoki Tsuji, Atsushi Saito, Nisha Mohd Rafiq

This study identifies synaptogyrin family proteins as key regulators of dopamine vesicle formation, overriding canonical synaptic vesicle size constraints and contributing to dopaminergic terminal vulnerability in Parkinson's disease.

bioRxiv · May 13, 2026 · PreprintNeuroscience