Author

Stanislav Tsitkov

Massachusetts Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Ernest FraenkeliD· 3 shared Velina KozarevaiD· 2 shared Aaron P. Frank· 1 shared Aneesh DondeiD· 1 shared Anna‐Leigh BrowniD· 1 shared Ashutosh DhingraiD· 1 shared Christian ThomasiD· 1 shared Clive Niels SvendseniD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersNeuroscience

Ernest FraenkelORCID

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3 papers

Recent·Most cited

Single-cell transcriptomic changes in oligodendroglial lineage cells derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation

Nasser Karmali, Wiebke Kessler, Mohammad Dehestani, Wenhua Sun, Layla Drwesh, Polina Volos, Stanislav Tsitkov, Ashutosh Dhingra, Christian Thomas, Salvador Rodrı́guez-Nieto, Julia Tietz, David Schafflick, Noémia Fernandes, Julia Fitzgerald, Ernest Fraenkel, , Vikas Bansal

The paper investigates transcriptomic changes in oligodendroglial lineage cells from PD patient-iPSCs with LRRK2-G2019S mutation, identifying altered pathways and signaling in OPCs and ODCs.

iScience · Jun 19, 2026Peer-reviewedNeuroscience

Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways

Velina Kozareva, Zhengde Liu, Keyana L. Blake, Yue Andy Qi, Sasha Rollinson, Sahba Seddighi, Mohammad Alsaidi, Stanislav Tsitkov, Mercedes Prudencio, Leonard Petrucelli, Dennis W. Dickson, Anna‐Leigh Brown, Pietro Fratta, Hong Joo Kim, J. Paul Taylor, , Sarah E. Kargbo-Hill

The paper identifies TDP-43-dependent molecular cascades in ALS/FTD by integrating multiomic data from iPSC-derived neurons and validates key genes through experimental assays.

bioRxiv · Sep 29, 2025 · PreprintNeuroscience

Disease related changes in ATAC-Seq of more than 450 iPSC-derived motor neuron lines from ALS patients and controls

Stanislav Tsitkov, Kelsey Valentine, Velina Kozareva, Aneesh Donde, Aaron P. Frank, Susan Lei, Jennifer E. Van Eyk, Steven M. Finkbeiner, Jeffrey D. Rothstein, Leslie Michels Thompson, Dhruv Sareen, Clive Niels Svendsen, Ernest Fraenkel

The paper analyzes ATAC-seq data from iPSC-derived motor neurons of ALS patients and controls to identify disease-specific chromatin accessibility changes and their predictive power for disease progression.

bioRxiv · Sep 11, 2023 · PreprintNeuroscience