Structural basis of DNA N6-adenine methylation in eukaryotes
Bei Nan, Wentao Yang, Liqin Nie, Dantong Wang, Mengyang Xu, Junhua Niu, Yuanyuan Wang, Wenjia Guan, Zhao Chen, Guiwu Zhuang, Shan Gao, Yifan Liu
This study determines the structural basis of DNA N6-adenine methylation by modeling the AMT1 complex and validating its function through mutagenesis.
bioRxiv · Jul 8, 2025 · PreprintMolecular Biology