Author

Liqin Nie

Qingdao National Laboratory for Marine Science and TechnologyORCID 0009-0002-5625-0474Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:protein structure prediction· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Bei NaniD· 2 shared Junhua NiuiD· 2 shared Shan GaoiD· 2 shared Dan ZhouiD· 1 shared Dantong WangiD· 1 shared Guiwu ZhuangiD· 1 shared Haoze YuiD· 1 shared Mengyang XuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersGenetics

Bei NanORCID

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2 papers

Recent·Most cited

GeneticsProceedings of the National Academy of SciencesPeer-reviewedMar 2, 2026

A distinct class of eukaryotic demethylases safeguards the positional fidelity of N6-methyladenine (6mA)

Junhua Niu, Haoze Yu, Yongqiang Liu…·Shan Gao

This study identifies DMT3 as a 6mA demethylase in unicellular eukaryotes and shows its role in maintaining transcriptional and developmental integrity by preventing ectopic 6mA deposition at TSS.

DOI 10.1073/pnas.2526398123

DNA methylationexperimental assay

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Molecular BiologybioRxivPreprintJul 8, 2025

Structural basis of DNA N6-adenine methylation in eukaryotes

Bei Nan, Wentao Yang, Liqin Nie…·Yifan Liu

This study determines the structural basis of DNA N6-adenine methylation by modeling the AMT1 complex and validating its function through mutagenesis.

DOI 10.1101/2025.07.08.663716

protein structuredeep learning

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