The LIF-LIFR Axis Promotes Liver Regeneration via Modulation of Angiogenesis and HGF Release from LSECs
Wenjing Zhou, Tanja Diemer, Hong Xin, Krishna Chaitanya Ginne, Naresh Kumar R N, Tommaso Mori, Nilima Biswas, Carlo Piermarocchi, Napoleone Ferrara
This paper identifies the LIF-LIFR axis as a key regulator of liver regeneration through LSECs, promoting angiogenesis and HGF release, and suggests therapeutic strategies for liver repair.
bioRxiv · Feb 25, 2026 · PreprintCell Biology