BiochemistrybioRxivPreprint
Bio-synthesis of 15N-Labeled G-Quadruplexes to Investigate the Structure and Interactions in the Cell Lysate using Nuclear Magnetic Resonance
Mengbing Zou, Fujia Tian, Wenwen Zheng…·Shenlin Wang
This paper introduces a method to produce 15N-labeled ssDNA for NMR studies of G-quadruplexes in cell lysates, revealing distinct ligand-binding behaviors in different environments.
DOI 10.1101/2025.11.03.685478