Direct neural perturbations reveal a dynamical mechanism for robust computation
Daniel J. O’Shea, Lea Duncker, Werapong Goo, Xulu Sun, Saurabh Vyas, Eric M. Trautmann, Ilka Diester, Charu Ramakrishnan, Karl A. Deisseroth, Maneesh Sahani, K.V. Shenoy
Optogenetic and electrical perturbations in primate motor cortex during reaching show that movement-related neural activity is governed by a self-contained, low-dimensional dynamical subspace causally linked to reach kinematics.
bioRxiv · Dec 16, 2022 · PreprintNeuroscience