Ilka Diester

This paper introduces an experimental protocol that extends the viability of acute brain slices beyond 36 hours, enabling long-term electrophysiological studies with reduced animal use and cost.

This study investigates how prefrontal cortex subsections interact during motor inhibition in rats using optogenetics and electrophysiology, finding that the prelimbic cortex acts as an input-dependent switch modulated by the infralimbic cortex.

The paper introduces FreiBox, an open-source behavioral setup for studying neuronal correlates of licking-based behavioral flexibility in mice using 1-photon calcium imaging.

This paper investigates the functional interactions between premotor and motor cortical areas in rats during goal-directed behavior, revealing differential roles of neuronal subpopulations in movement preparation and execution.

Optogenetic and electrical perturbations in primate motor cortex during reaching show that movement-related neural activity is governed by a self-contained, low-dimensional dynamical subspace causally linked to reach kinematics.

Similarities in neural population structures across the sensorimotor cortex enable generalization across animals in the decoding of unconstrained behavior.

This paper introduces a framework for 3D pose estimation in freely moving rats to remove movement artifacts from neural recordings, revealing new insights into motor cortex neuron tuning.

This paper develops thin optical fibers and integration techniques to enable large-scale neuronal recordings and ultrafast optogenetic inhibition in freely moving animals.

This paper introduces a multifunctional optrode for optogenetics, enabling simultaneous drug delivery, optical stimulation, and electrophysiological recording in freely moving rats.

This study shows that spontaneous beta-bursts in rat somatosensory cortex compete with external stimuli, reducing detection performance.

The paper uses optogenetics to show that cortical resonance selectively transmits coherent input components through feedback inhibition and spike-frequency adaptation.

This study identifies distinct time-scale dynamics in motor planning and execution in the rat sensorimotor cortex using high-pass filtering and optogenetic validation.

The paper shows that gamma-band input specifically drives spike output in neuronal networks through optogenetic stimulation and analysis of temporal responses.

FreiPose is a deep learning framework for precise 3D motion capture of animals, showing high accuracy and reliability in tracking rats during electrophysiological and optogenetic experiments.

This paper introduces a real-time system to detect neural oscillation bursts in rats and shows its use in neurofeedback training to increase beta-band burst-rate.

This paper investigates gamma-band resonance in visual cortex using optogenetic stimulation and electrophysiological recordings in anesthetized cats, finding that circuits resonate most strongly to gamma-band inputs.

The paper shows that gamma-band activity in macaque V4 and cat 21a rhythmically modulates neuronal responses and behavioral reaction times through gain modulation.