Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate neutrophilic allergic airways disease.
Vijay Raaj Ravi, Filiz T. Korkmaz, Carolina Lyon De Ana, Lu Lu, Feng-Zhi Shao, Christine V. Odom, Kimberly A. Barker, Aditya Ramanujan, Emma N. Niszczak, Wesley N. Goltry, Ian M.C. Martin, Catherine T. Ha, Lee J. Quinton, Matthew R. Jones, Alan Fine, , Anukul T. Shenoy
This study identifies lung CD4+ resident memory T cells and their interaction with airway secretory cells as key regulators of neutrophilic allergic airways disease in mice and humans.
Cell Reports · Feb 17, 2025Peer-reviewedImmunology