Author

William B. Lynch

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 4

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Britahny M. Baskin· 3 shared Camron D. BryantiD· 3 shared Jacob A. BeierleiD· 3 shared Sophia A. MiracleiD· 3 shared Emily J. Yao· 2 shared Kayla T. Richardson· 2 shared Kelly K. WingfieldiD· 2 shared Amanda Lea SharpeiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Britahny M. Baskin

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4 papers

Recent·Most cited

Validation studies and multi-omics analysis of Zhx2 as a candidate quantitative trait gene underlying brain oxycodone metabolite (oxymorphone) levels and behavior

William B. Lynch, Sophia A. Miracle, Stanley I. Goldstein, Jacob A. Beierle, Rhea Bhandari, Ethan Gerhardt, Ava D. Farnan, Binh-Minh Nguyen, Kelly K. Wingfield, Ida Kazerani, Gabriel A. Saavedra, Olga Averin, Britahny M. Baskin, Martin T. Ferris, Christopher A. Reilly, , Camron D. Bryant

The paper validates Zhx2 as a quantitative trait gene influencing brain oxymorphone levels and opioid behavior through genetic and multi-omics analyses in mice.

The Journal of Pharmacology and Experimental Therapeutics · May 1, 2025Peer-reviewedNeuroscience

The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female mice

Kelly K. Wingfield, Teodora Misic, Kaahini Jain, Carly S. McDermott, Nalia M. Abney, Kayla T. Richardson, Mia B. Rubman, Jacob A. Beierle, Sophia A. Miracle, Emma J Sandago, Britahny M. Baskin, William B. Lynch, Kristyn N. Borrelli, Emily J. Yao, Elisha M. Wachman, Camron D. Bryant

This study examines USV profiles and kappa opioid receptor involvement in neonatal opioid withdrawal in female mice, finding increased Complex 3 syllables and female-specific KOR system activation.

Psychopharmacology · Sep 30, 2024Peer-reviewedNeuroscience

The striatal heterogeneous nuclear ribonucleoprotein H mRNA targetome associated with methamphetamine administration and behavior

Qiu T. Ruan, William B. Lynch, Rebecca H. Cole, Michael A. Rieger, Britahny M. Baskin, Sophia A. Miracle, Jacob A. Beierle, Emily J. Yao, Jiayi Wu Cox, Amarpreet K. Kandola, Kayla T. Richardson, Melanie M. Chen, Julia C. Kelliher, R.K. Babbs, Peter E.A. Ash, , Camron D. Bryant

The paper identifies a dynamic hnRNP H RNA targetome in the striatum that responds to methamphetamine, affecting gene expression and behavior.

bioRxiv · Jul 6, 2021 · PreprintNeuroscience

Depression of substantia nigra dopamine transmission is driven by retrograde neurotensin release and is enhanced by methamphetamine self-administration

Christopher W. Tschumi, Ramaswamy Sharma, William B. Lynch, Amanda Lea Sharpe, Michael J. Beckstead

The paper shows that neurotensin release from dopamine neurons drives long-term depression of D2R synaptic currents, which is enhanced by methamphetamine self-administration.

bioRxiv · Aug 28, 2019 · PreprintNeuroscience