Qiu T. Ruan

Sex differences in behavioral and brainstem transcriptomic neuroadaptations following neonatal opioid exposure in outbred mice

This study investigates sex differences in behavioral and brainstem transcriptomic changes in mice exposed to neonatal opioids, finding sex-specific neuroadaptations linked to NOWS-like behaviors.

The striatal heterogeneous nuclear ribonucleoprotein H mRNA targetome associated with methamphetamine administration and behavior

The paper identifies a dynamic hnRNP H RNA targetome in the striatum that responds to methamphetamine, affecting gene expression and behavior.

Fentanyl-induced antinociception, reward, reinforcement, and withdrawal in Hnrnph1 mutant mice

This study investigates the role of Hnrnph1 in fentanyl-induced behaviors, finding reduced sensitivity and reward in mutants with sex-specific effects.

5' UTR variants in the quantitative trait gene Hnrnph1 support reduced 5' UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity

The paper identifies 5' UTR variants in Hnrnph1 that reduce 5' UTR usage and hnRNP H protein levels, linking these changes to reduced methamphetamine sensitivity.

A mutation in Hnrnph1 that decreases methamphetamine-induced reinforcement, reward, and dopamine release and increases synaptosomal hnRNP H and mitochondrial proteins

This study identifies a mutation in Hnrnph1 that reduces methamphetamine-induced reinforcement, reward, and dopamine release while increasing synaptic hnRNP H and mitochondrial proteins in mice.

Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake: Implications for Prader-Willi Syndrome

This study shows that Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake in a parent-of-origin and genetic background-dependent manner in mice.

Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation

The paper examines changes in hnRNP H localization in primary rat cortical neurons after D1 dopamine receptor activation, finding increased nuclear immunostaining of the C-terminal domain without changes in protein levels.