Author

William Dennis

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:imaging· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Christina Ford· 2 shared Elizabeth BrunkiD· 2 shared Jingting CheniD· 2 shared Aarav MehtaiD· 1 shared Damien GuilbaudiD· 1 shared Darby ChengiD· 1 shared Jacob Fessler· 1 shared Jillann A. Madren· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Christina Ford

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses

Kohen Goble, Aarav Mehta, Damien Guilbaud, Jacob Fessler, Jingting Chen, William Nenad, Christina Ford, Oliver Cope, Darby Cheng, William Dennis, Nithya Gurumurthy, Yue Wang, Kriti Shukla, Elizabeth Brunk

This study introduces an automated pipeline for detecting and quantifying ecDNA in FISH images to analyze drug response mechanisms in cancer cells.

Frontiers in Pharmacology · Feb 3, 2025Peer-reviewedCancer Biology

A Standardized Protocol for Sample Preparation for Scanning Electron Microscopy (SEM) to Visualize Extrachromosomal DNA (ecDNA)

Jillann A. Madren, Jingting Chen, William Dennis, Christina Ford, Kristen White, Elizabeth Brunk

This paper presents a standardized protocol for visualizing extrachromosomal DNA (ecDNA) using scanning electron microscopy (SEM) in human cancer cell lines.

bioRxiv · Aug 24, 2023 · PreprintMolecular Biology