Author

Christina Ford

University of North Carolina at Chapel Hill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Elizabeth BrunkiD· 4 shared Jingting CheniD· 4 shared Aarav MehtaiD· 3 shared Yue WangiD· 3 shared Jacob Fessler· 2 shared Kohen Goble· 2 shared Oliver Cope· 2 shared Santiago HaaseiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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4 shared papersGenomics

Elizabeth BrunkORCID

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Author profile →

4 papers

Recent·Most cited

Extrachromosomal DNA Gives Cancer a New Evolutionary Pathway

Yue Wang, Oliver Cope, Jingting Chen, Aarav Mehta, Dalia Fleifel, Christina Ford, Poorya Behnamie, Molly Murray, Santiago Haase, Saygin Gulec, Logan Slade, Tim C. Elston, Philip M. Spanheimer, Caroline A Tomblin, Alison M. Rojas, , Elizabeth Brunk

The paper shows that ecDNA allows tumors to adapt rapidly by maintaining a spectrum of gene expression levels across cells, rather than relying on clonal expansion.

bioRxiv · Apr 26, 2025 · PreprintGenomics

Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses

Kohen Goble, Aarav Mehta, Damien Guilbaud, Jacob Fessler, Jingting Chen, William Nenad, Christina Ford, Oliver Cope, Darby Cheng, William Dennis, Nithya Gurumurthy, Yue Wang, Kriti Shukla, Elizabeth Brunk

This study introduces an automated pipeline for detecting and quantifying ecDNA in FISH images to analyze drug response mechanisms in cancer cells.

Frontiers in Pharmacology · Feb 3, 2025Peer-reviewedCancer Biology

CytoCellDB: A Resource Database For Classification and Analysis of Extrachromosomal DNA in Cancer

Jacob Fessler, Stephanie Ting, Hong Yi, Santiago Haase, Jingting Chen, Saygin Gulec, Yue Wang, Nathan Smyers, Kohen Goble, Danielle Cannon, Aarav Mehta, Christina Ford, Elizabeth Brunk

CytoCellDB is a database that expands the number of cancer cell lines with ecDNA annotations, enabling analysis of ecDNA in relation to molecular data and drug responses.

bioRxiv · Dec 18, 2023 · PreprintGenomics

A Standardized Protocol for Sample Preparation for Scanning Electron Microscopy (SEM) to Visualize Extrachromosomal DNA (ecDNA)

Jillann A. Madren, Jingting Chen, William Dennis, Christina Ford, Kristen White, Elizabeth Brunk

This paper presents a standardized protocol for visualizing extrachromosomal DNA (ecDNA) using scanning electron microscopy (SEM) in human cancer cell lines.

bioRxiv · Aug 24, 2023 · PreprintMolecular Biology