Yue Wang

This paper uses AI/ML to annotate genomic variants in breast cancer, identifying new actionable mutations and functional consequences beyond known drivers.

The paper shows that ecDNA allows tumors to adapt rapidly by maintaining a spectrum of gene expression levels across cells, rather than relying on clonal expansion.

This paper introduces a multimodal framework to identify drug-responsive subpopulations in triple-negative breast cancer by integrating bulk and single-cell transcriptomics data.

This study introduces an automated pipeline for detecting and quantifying ecDNA in FISH images to analyze drug response mechanisms in cancer cells.

CytoCellDB is a database that expands the number of cancer cell lines with ecDNA annotations, enabling analysis of ecDNA in relation to molecular data and drug responses.