Long-read transcriptome assembly reveals vast transcriptional complexity in the placenta associated with metabolic and endocrine function
Sean T. Bresnahan, Hannah E. J. Yong, Aryun Nemani, William H. Wu, Sierra Lopez, Jerry Kok Yen Chan, Frédérique White, Pierre‐Étienne Jacques, Marie‐France Hivert, Shiao-Yng Chan, Michael I. Love, Jonathan Yinhao Huang, Arjun Bhattacharya
The paper uses long-read RNA-seq to create a comprehensive placental transcriptome reference, revealing high transcriptional complexity and identifying novel isoforms associated with metabolic and endocrine functions in gestational diabetes.
Nature Communications · Apr 2, 2026Peer-reviewedGenomics