The role of VISTA engagement in limiting neutrophil-mediated inflammation
Elizabeth C. Nowak, Jiannan Li, Zachary T. Peters, Lindsay K. Mendyka, Mohamed A. ElTanbouly, Wilson L. Davis, Petra A. Sergent, Janet Louise Lines, Nicole C. Smits, Rodwell Mabaera, Shibani Rajanna, Catherine Carrière, Brent H. Koehn, Jeremy R. Allred, Bruce R. Blazar, , Sladjana Skopelja‐Gardner
This study shows that agonist anti-VISTA antibodies reduce neutrophil inflammation by decreasing their peripheral accumulation and increasing liver cell death, improving arthritis in mice.
The Journal of Immunology · Jun 26, 2025Peer-reviewedImmunology