Novel HIV-1 fusion peptide immunogens using glycan-engineered alphavirus-like particles
Seo-Ho Oh, Dedeepya R. Gudipati, Wei Shi, Peng Zhao, Winston Wu, Jeffrey C. Boyington, Hardik K. Nariya, Emily G. McGhee, Tala Azzam, Vedhika Raghunathan, Chumeng Yang, Catherine F. Yang, Christian R. Lee, J Kim, Tongqing Zhou, , Rui Kong
This paper develops glycan-engineered alphavirus-like particles as HIV-1 fusion peptide immunogens, showing improved antibody responses and neutralization against multi-clade HIV-1.
npj Vaccines · Nov 14, 2025Peer-reviewedImmunology