Stabilized D2R G-protein coupled receptor oligomers identify multi-state β-arrestin complexes
Katie L. Sharrocks, Francesca Fanelli, Yewei Liu, Annabelle J. Milner, Wu Yining, Bernadette Byrne, Aylin Carla Hanyaloglu
This study identifies D2R receptor mutants that stabilize oligomers and show biased recruitment of β-arrestin-2, leading to altered signaling outcomes.
Nature Communications · Oct 2, 2025Peer-reviewedCell Biology