D- and L-Lactate enhance intestinal barrier function via activation of an apical HCAR1/Giα pathway in a human colonic epithelial cell model
Annabelle J. Milner, Priyanka Anujan, Gary Steven Frost, Aylin Carla Hanyaloglu
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Imperial College LondonORCID 0009-0003-0124-0057Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
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Annabelle J. Milner, Priyanka Anujan, Gary Steven Frost, Aylin Carla Hanyaloglu
Yusman Manchanda, Natalie Sean Man Wong, Annabelle J. Milner, Alejandra Tomás
This study shows that phosphorylation of specific C-terminal serine doublets in the GLP-1R is critical for receptor signaling in β-cells, with basal phosphorylation influencing receptor dynamics and signaling outcomes.
Katie L. Sharrocks, Francesca Fanelli, Yewei Liu…·Aylin Carla Hanyaloglu
This study identifies D2R receptor mutants that stabilize oligomers and show biased recruitment of β-arrestin-2, leading to altered signaling outcomes.