TMEM63B functions as a mammalian thirst receptor
Wenjie Zou, Xingyu Chen, Jiamin Ruan, Siqi Deng, Huize Wang, Wuqiang Zhan, Jingxin Wang, Zhiyong Liu, Zhiqiang Yan
This study identifies TMEM63B as a mammalian thirst receptor in the subfornical organ, showing it mediates osmotic and dehydration-induced thirst through ion channel activity.
bioRxiv · Feb 1, 2024 · PreprintNeuroscience