Acrylamide Induces Protein Aggregation in CNS through Suppression of FoxO1-mediated Autophagy.
X.-B. He, H. Huang, Y. Wu, F. Guo
This study shows acrylamide induces proteotoxic stress in CNS by suppressing FoxO1-mediated autophagy, leading to protein aggregation and neurodegeneration.
bioRxiv · Jul 29, 2022 · PreprintPathology