Author

X.-c. Bai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Organism:mouse· 2 Research Focus:protein structure prediction· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1

Frequent Co-Authors

E. Choi· 1 shared H. Yu· 1 shared J. Li· 1 shared J. She· 1 shared J. Wu· 1 shared N. X. Nguyen· 1 shared V. K. Mootha· 1 shared W. Wang· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

E. Choi

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Author profile →

3 papers

Recent·Most cited

Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor

J. Li, J. Wu, X.-c. Bai, E. Choi

This study reports cryo-EM structures of modified IGF1R and IR complexes, showing that disulfide-linked CTs are critical for receptor activation and signaling.

bioRxiv · Jul 6, 2022Cell Biology

Characterization of the subunit composition and structure of native adult glycine receptors

H. Yu, X.-c. Bai, W. Wang

The paper characterizes the subunit composition and structure of native adult glycine receptors, showing a 4:1 stoichiometry of 2 and β subunits and their functional implications.

bioRxiv · May 17, 2021Biophysics

Structural insights into the Ca 2+-dependent gating of the human mitochondrial calcium uniporter

Y. Jiang, Y. Wang, Y. Han, J. She, N. X. Nguyen, V. K. Mootha, X.-c. Bai

This study presents EM structures of the human mitochondrial calcium uniporter holocomplex with and without Ca2+, showing how Ca2+ affects its assembly and channel pore blockage.

bioRxiv · Jul 2, 2020Biochemistry