Hyd ubiquitinates the NF-κB co-factor Akirin to activate an effective immune response in Drosophila
A. Cammarata-Mouchtouris, X.-H. Nguyen, F. Bonnay, A. Goto, A. Orian, M.-O. Fauvarque, M. Boutros, J.-M. Reichhart, N. Matt
This study identifies Hyd as an E3-ubiquitin ligase that ubiquitinates Akirin to enhance Relish binding and activate immune effector genes in Drosophila.
bioRxiv · Jul 20, 2018Immunology