Fezf2 regulates differentiation of Aire-expressing and post-Aire mimetic epithelial populations maintaining thymic homeostasis
Joe Germino, Xian Liu, Yi Wang, Jared Balolong, Vera Tang, Im‐Hong Sun, Yanzhen Nie, Jeremiah Tsyporin, Irina Proekt, Kristin Rattay, Vasilis Ntranos, Mark Stuart Anderson, Bin Chen, James Morgan Gardner, Corey N. Miller
This study shows Fezf2 regulates mTEC lineage commitment and homeostasis, with transcriptional repression playing a key role in maintaining thymic epithelial populations.
bioRxiv · Jan 1, 2026 · PreprintImmunology