Author

Yi Wang

University of California, San FranciscoORCID 0000-0002-6074-0532Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Biology Disciplines

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Genetics· 1 Genomics· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Christian VaisseiD· 2 shared Nadav AhituviD· 2 shared Navneet Kaur MatharuiD· 2 shared Aaron I. HardiniD· 1 shared Adélaïde BernardiD· 1 shared Bin CheniD· 1 shared Brian G. DrewiD· 1 shared Corey N. MilleriD· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersGenomics

Christian VaisseORCID

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Author profile →

4 papers

Recent·Most cited

Diet- and metabolic state-dependent remodeling of the mouse brain lipidome

Adélaïde Bernard, Kevin Huynh, Jen Xin Fach, Hang Yi Woo, He Liu, Yingying Liu, Natalie A. Mellet, Peter Meikle, Brian G. Drew, Y. Wang

This study shows that the mouse brain lipidome changes with diet and metabolic state, particularly highlighting the impact of high-fat diets on lipid remodeling in the hypothalamus and brainstem.

bioRxiv · Mar 2, 2026 · PreprintPhysiology

Fezf2 regulates differentiation of Aire-expressing and post-Aire mimetic epithelial populations maintaining thymic homeostasis

Joe Germino, Xian Liu, Yi Wang, Jared Balolong, Vera Tang, Im‐Hong Sun, Yanzhen Nie, Jeremiah Tsyporin, Irina Proekt, Kristin Rattay, Vasilis Ntranos, Mark Stuart Anderson, Bin Chen, James Morgan Gardner, Corey N. Miller

This study shows Fezf2 regulates mTEC lineage commitment and homeostasis, with transcriptional repression playing a key role in maintaining thymic epithelial populations.

bioRxiv · Jan 1, 2026 · PreprintImmunology

Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation

Fumitaka Inoue, Walter L. Eckalbar, Yi Wang, Karl K. Murphy, Navneet Kaur Matharu, Christian Vaisse, Nadav Ahituv

The paper maps genomic and epigenomic features of leptin-responsive hypothalamic neurons and identifies regulatory elements overlapping obesity-associated SNPs.

Nature Metabolism · Apr 8, 2019Peer-reviewedGenomics

Promoter Or Enhancer Activation By CRISPRa Rescues Haploinsufficiency Caused Obesity

Navneet Kaur Matharu, Sawitree Rattanasopha, Lenka Maliskova, Yi Wang, Aaron I. Hardin, Christian Vaisse, Nadav Ahituv

This study shows CRISPRa can rescue Sim1 haploinsufficiency-induced obesity by targeting the promoter or enhancer, demonstrating tissue-specific upregulation of Sim1.

bioRxiv · May 22, 2017 · PreprintGenetics