Author

Xiang Ruan

Western University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alyssa WuiD· 1 shared Courtney VossiD· 1 shared Ilka U. HeinemanniD· 1 shared Jenica H. KakadiaiD· 1 shared Kyle YangiD· 1 shared Mallory I. Frederick· 1 shared Owen F.J. HoveyiD· 1 shared Quan M. QuachiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alyssa WuORCID

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1 paper

Recent·Most cited

LIN28A-Dependent Kinome and Phosphoproteome Reprogramming Promotes Imatinib Resistance

Owen F.J. Hovey, Mallory I. Frederick, Quan M. Quach, Jenica H. Kakadia, Alyssa Wu, Kyle Yang, Tingting Wu, Xiang Ruan, Tomonori Kaneko, Courtney Voss, Ilka U. Heinemann, Shawn S.‐C. Li

This study identifies LIN28A as a mediator of imatinib resistance in CML by reprogramming the kinome and phosphoproteome, with potential therapeutic implications for overcoming resistance.

Molecular & Cellular Proteomics · Jan 20, 2026Peer-reviewedCancer Biology