Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression
Qi-Xin Zhang, Tianzi Liu, Xinxin Guo, Jianxin Zhen, Mengyuan Yang, Saber Khederzadeh, Fang Xiao Zhou, Xiaotong Han, Qiwen Zheng, Peilin Jia, Xiaohu Ding, Mingguang He, Xin Zou, Jia-Kai Liao, Hongxin Zhang, , Guo‐Bo Chen
This paper introduces encG-reg, an encrypted genotype regression method that identifies relatives across cohorts without sharing raw data, achieving accuracy comparable to traditional methods.
PLoS Genetics · Jan 11, 2024Peer-reviewedGenetics