Qi-Xin Zhang

UK BioCoin: Swift Trait-Specific Summary Statistics Regression for UK Biobank

UK BioCoin enables trait-specific covariate adjustment for UK Biobank summary statistics without individual-level data, achieving high correlation with full GWAS results.

Analytical and computational solution for the estimation of SNP-heritability in biobank-scale and distributed datasets

This paper presents an analytical solution for estimating SNP-heritability in biobank-scale and distributed datasets, achieving high precision and efficiency.

An Atlas of Linkage Disequilibrium Across Species

The paper introduces two LD estimation algorithms to create high-resolution LD grids across species, revealing evolutionary patterns and population structure.

DeepKin: precise estimation of in-depth relatedness and its application in UK Biobank

deepKin estimates relatedness with statistical inference and applies it to UK Biobank data, identifying significant relatives and geographic patterns.

Searching across-cohort relatives in 54,092 GWAS samples via encrypted genotype regression

This paper introduces encG-reg, an encrypted genotype regression method that identifies relatives across cohorts without sharing raw data, achieving accuracy comparable to traditional methods.