Author

Xiaowen Tian

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 2 Research Focus:benchmarking· 1 Assay:clinical cohort / trial· 1 Research Focus:database / resource· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Achilleas PitsillidesiD· 1 shared Adolfo CorreaiD· 1 shared Albert V. SmithiD· 1 shared Álvaro AlonsoiD· 1 shared Amol Carl ShettyiD· 1 shared André CorveloiD· 1 shared Andrew D. JohnsoniD· 1 shared Anna KöttgeniD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Achilleas PitsillidesORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Evaluating computational approaches for comparison of protein expression across cancer indications

Jixin Wang, Xiaowen Tian, Wen Yu, Ben Pullman, John Bullen, Elaine M. Hurt, Wenyan Zhong

The paper evaluates normalization strategies for creating a pan-cancer protein expression dataset from CPTAC, finding global quantile normalization most effective for cross-cohort comparisons.

bioRxiv · Aug 26, 2024 · PreprintBioinformatics

Estimating the genome-wide mutation rate from thousands of unrelated individuals

Xiaowen Tian, Ruoyi Cai, Sharon R. Browning

The paper estimates genome-wide mutation rates from population data using IBD segments, finding consistent rates across three populations.

The American Journal of Human Genetics · Nov 11, 2022Peer-reviewedGenetics

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Daniel Taliun, Daniel Harris, Michael D. Kessler, Jedidiah Carlson, Zachary A. Szpiech, Raul Torres, Sarah A. Gagliano Taliun, André Corvelo, Stephanie M. Gogarten, Hyun Min Kang, Achilleas Pitsillides, Jonathon LeFaive, Seung‐been Lee, Xiaowen Tian, Brian L. Browning, , Ruth J. F. Loos

Over 400 million variants, 97% below 1% frequency, emerge from deep whole-genome sequencing of 53,831 diverse TOPMed participants; TOPMed haplotypes enable imputation down to ~0.01% frequency.

Nature · Feb 10, 2021Peer-reviewedGenomics✦ In-depth digest