Yeast replicative aging leads to permanent cell cycle arrest in G1 effectuated by the start repressor Whi5
Jing Yang, Ziwei Wang, Xili Liu, Hao Li, Qi Ouyang
This study shows that yeast replicative aging causes permanent G1 cell cycle arrest mediated by the Whi5 repressor, with increased Whi5 concentration correlating with G1 lengthening and cell death.
bioRxiv · Jun 22, 2018 · PreprintCell Biology